Clinacanthus nutans Lindau is known as snake grass belonging to the Acanthaceae family. This plant has diverse and potential medicinal uses. PDF | Clinacanthus nutans is widely known in traditional medicine in Malaysia and Thailand due to its medicinal properties in treating skin rashes, insect and. Family Name: Acanthaceae. Synonyms: Clinacanthus burmanni. Common Names: Sabah Snake Grass. Chinese Name: 优顿草.

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In addition, Clinacanthus Nutans leaves extracts are adding another soothing effect as follows. Songklanakarin Journal of Science and Technology.

Please review our privacy policy. Significant inhibition of cell proliferation was shown in HeLa and K cells after treated with the C. Thus, interest has been shifted to study traditional herbs as alternate anticancer regimens due to its multitargeted characteristics.

Briefly spread with circular gesture. This effect is likely to enable cancer cells to evade ROS mediated apoptosis. Figure 1 showed the galvinoxyl radical scavenging activity of three types of extractions. The authors thank Mrs. Hence, we sought to evaluate Clinacanthus nutans Lindau for its potential to be used as natural nutraceuticals for cancer prevention and treatment. National Center for Biotechnology Information clinacanthuz, U.

Table 2 Phyto-constituents identified in the chloroform extract of the leaves of C.

Free radicals and antioxidants: Previous reports suggested that 1, 2-benzenedicarboxylic acid, mono 2-ethylhexyl ester has anti-microbial activity [ 20 ]. Despite Lemon Import products are not medicine, the use of herbs based actives is in line with this tradition. Asian Pacific Journal of Tropical Medicine. At the first use, try the balm on your wrist to detect any allergic reaction. The filtrates in chloroform and methanol were dried by using rotary evaporator, while filtrates c,inacanthus distilled water were dried with a freeze drier.


In conclusion, chloroform extract of C.

Family business since 4 generation, Cher-aim provides wellness products made with Thai medicinal herbs. However the use has also been limited by genomic instability and drug resistance characteristics in certain cancer cells. A partner in daily life.

Clinacanthus nutans CN leaves have previously been known to have anti-inflammatory [ 28 ] and antiviral properties [ 2930 ].

A small quantity is enough to provide a warm effect within a few minutes. In other projects Wikimedia Commons Wikispecies. This balm may also be spread on calves, wrists or on back of neck to reduce risk of insect clinacantgus.

In conclusion, CN extracts possess antioxidant and antiproliferative properties against cultured cancer cell lines, suggesting an alternate adjunctive regimen for cancer prevention or treatment.

Clinacanthus nutans – Wikipedia

All the assays were carried out in triplicate and in three independent tests. Hence, the main objective in this study was to examine the antioxidant and cytotoxicity effects of C.

Past studies have shown that imbalance cellular redox homeostasis with elevated free radical production is one of the common causes of cancer initiation and progression and many other diseases [ 21 ].

Thereby, Clinacanthus Nutans is one of these plants, widely used in traditional thai medicine to ease skin irritations like insects or snakes bites, scorch or sting. Soothing balm 22g Clinacanthus Nutans Balm 22g Ref.: Antioxidant activity and protective effect against oxidative hemolysis of Clinacanthus nutans Burm.

Despite all the known biological activities from previous work, emerging lay testimonies and Malaysian newspaper reports suggested that CN possesses antitumor effects and had saved many of various cancers. However, CNA showed the lowest activity with antioxidant capacity value Therefore, the concept of multitargeted therapy is introduced to exploit the use of single regimen to exert complex synergistic and antagonistic effects to act on multiple pathophysiological pathways in order to achieve optimal therapeutic outcome.

Free radicals, metals and antioxidants in oxidative stress-induced cancer. The extracts in all three solvents were collected separately in clean glass bottles. With advances in cancer research, many molecular targeted drugs have been introduced and showed promising outcome with little side effects. Wiseman H, Halliwell B. This article has been cited by other articles in PMC. To ease harms in daily life: Ngah are acknowledged for technical assistance. Asian Journal of Surgery.


This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. It was observed that only CNA has the ability to scavenge nitric oxide radical and was in the concentration dependent manner.

However, no effect was observed in IMR 32 cell lines. For external use only on unwounded skin.

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Percentage scavenging activity of nitric oxide radicals in response to C. International Journal of Molecular Sciences. Evidence has shown that oncogene activation, increased metabolic activity, and mitochondrial malfunction are common causes which njtans responsible for substantial surge in cellular RONS level [ 8 ].

Chloroform extract exerted the highest antiproliferative effect on K Acknowledgments The authors thank Mrs. Antiproliferative activity of the three extracts was examined by using MTT assay [ 19 ]. DPPH and galvinoxyl radical scavenging activity of various solvent extracts of Clinacanthus nutans leaves.

A review of the medicinal uses, pharmacology and phytochemistry”. Thus, scavenging the free radicals with antioxidant may prove an alternate strategy to protect normal healthy cells from DNA damage and limit the progression of cancer cells.